Dr. Zahra Keshavarz Motamed

Dr. Zahra Keshavarz Motamed

Assistant Professor

McMaster University
Department of Mechanical Engineering
Hamilton, Ontario, Canada L8S 4L7

Office: JHE A416 (Mail to JHE-310)
Email: motamedz@mcmaster.ca
Voice: (905) 525-9140 x26997

 

  • B.Sc., M.Sc., Mechanical Engineering, Sharif University of Technology, Tehran, Iran (1998, 2001)
  • PhD, Mechanical Engineering, Concordia University, Montreal, Canada, 2012
  • PDF, Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA, 2016; University of Montreal/Laval University, Montreal, Canada, 2014

 

Brief Bio

Dr. Motamed will be joining the Department of Mechanical Engineering at McMaster University as an assistant professor in January 2017. Currently, she is a postdoctoral fellow in the Institute for Medical Engineering & Science at MIT (Cambridge, USA) and Harvard-MIT Biomedical Engineering Center (2014-2016). She received her Ph.D. degree in mechanical engineering from Concordia University (Montreal, Canada) in 2012 where she was a part-time/adjunct faculty member from 2013 to 2014. Furthermore, she was a postdoctoral fellow in University of Montreal/Laval University. Her primary research work led to 40 refereed journals and conference papers. She is a scientific consultant to medical device companies. She also has 8 years of industrial experience in the automotive design sector with a proven record of leadership and project and team management.

Research Interests

Cardiovascular disease is the leading cause of death globally, taking more lives than all forms of cancer combined. Despite advancement in surgical/interventional techniques, many cardiovascular patients do not respond favorably to treatments and consequently life expectancy for them remains reduced due to short- and long-term morbidity. Sources of morbidity can be explained on the basis of abnormal hemodynamics and biomechanics that lead to initiation and progression of cardiovascular diseases.

Dr. Motamed’s research interests are in the areas of translational and basic cardiovascular mechanics. In her multidisciplinary research, she uses and advances knowledge in biomechanics, fluid mechanics, solid mechanics, medical imaging and mathematical modelling. A major part of her work is dedicated to development of advanced numerical algorithms for simulation of cardiovascular mechanics and patient-specific modelling using medical imaging and clinical measurements with the following objectives:

- To understand the mechanisms underlying cardiovascular pathologies in order to provide life-saving answers to clinical questions
- To develop most needed quantitative non-invasive diagnostic methods for cardiovascular disease
- To design, develop, evaluate and optimize cardiovascular devices such as transcatheter heart valves and vascular stents
- To lead multidisciplinary collaborative efforts to translate engineering-based findings and developments into clinical practice

Due to the interdisciplinary nature of her research, Dr. Motamed established a very strong collaborative network with other researchers such as clinical scientists, surgeons, cardiologists, engineers and applied mathematicians in Canada, USA and Europe as well as with medical-device companies.

Announcement:

Dr. Keshavarz Motamed will be joining the Department of Mechanical Engineering in January of 2017.

Selected Awards & Honours

- American Heart Association (AHA), Postdoctoral Fellowship, USA, 2016
- Fonds de la Recherche du Québec-Santé (FRSQ) Renewal, Postdoctoral Fellowship, Canada, 2016
- Natural Sciences and Engineering Research Council of Canada (NSERC), Postdoctoral Fellowship, Canada, 2014
- Fonds de la Recherche du Québec-Santé (FRSQ), Postdoctoral Fellowship, Canada, 2014
- Visiting Scholars Fellowship, Natural Sciences and Engineering Research Council of Canada (NSERC), Postdoctoral Fellowship, Canada, 2014
 - Fonds de la Recherche du Québec-Nature et Technologies (FQRNT), Postdoctoral Fellowship, Canada, 2013
- Amelia Earhart Fellowship, Zonta International Foundation for women in engineering, USA, 2011
- PhD Thesis Completion Award, Doctoral award, Canada, 2011
- Campaign for A New Millennium, Doctoral award, Canada, 2011
- Power Corporation of Canada, Doctoral award, Canada, 2011
- Carolyn & Richard Renaud Teaching, Doctoral award, Canada, 2010
- Power Corporation of Canada, Doctoral award, Canada, 2010


Selected Publications

- Z. Keshavarz-Motamed, F. Rikhtegar Nezami, R. A. Partida, K. Nakamura, P. V. Staziaki, E. Ben-Assa, B. Ghoshhajra, A. B. Bhatt, E. R. Edelman. (2016). Elimination of trans-coarctation pressure gradients has no impact on left ventricular function or aortic shear stress post intervention in patients with mild coarctation. JACC: Cardiovascular Interventions. 10.1016/j.jcin.2016.06.054, in press.
- Z. Keshavarz-Motamed, E. Edelman, P. K. Motamed, J. Garcia, N. Dahdah, L. Kadem. (2015). The role of aortic compliance in determination of coarctation severity: lumped parameter modeling, in vitro study and clinical evaluation. Journal of Biomechanics. 48(16): 4229-4237.
- Z. Keshavarz-Motamed, P. K. Motamed, N. Maftoon. (2015). Non-invasive determination of aortic valve trans-catheter pressure gradient: an analytical model. Medical Engineering & Physics. 37(3): 321-327.
- E. Benevento, A. Dejebbari, Z. Keshavarz-Motamed, R. Cecere, L. Kadem. (2015). Flow distribution in aortic valve bypass: a mathematical modeling approach. PLoS One. 10(4): e0123000.
- Z. Keshavarz-Motamed, J. Garcia, E. Gaillard, R. Capoulade, F. LeVen, G. Cloutier, L. Kadem, P. Pibarot. (2014). Non-invasive determination of left ventricular workload in patients with aortic stenosis using magnetic resonance imaging and Doppler echocardiography. PLoS One. 9(1): e86793.
- Z. Keshavarz-Motamed, Y. Saijo, Y. Majdouline, J. Ohayon, G. Cloutier. (2014). Coronary artery atherectomy stabilizes plaque shear strains: an endovascular elastography imaging study. Atherosclerosis. 235(1): 140-149.
- Z. Keshavarz-Motamed, J. Garcia, E. Gaillard, N. Maftoon, G. Di Labbio, G. Cloutier, L. Kadem. (2014). Effect of coarctation of the aorta and bicuspid aortic valve on flow dynamics and turbulence in the aorta using particle image velocimetry. Experiments in Fluids. 55: 1696.
- Y. Majdouline, J. Ohayon, Z. Keshavarz-Motamed, M. H. Roy Cardinal, D. Garcia, L. Allard, S. Lerouge, F. Arsenault, G. Soulez, G. Cloutier. (2014). Endovascular shear strain elastography for detection and characterization the severity of atherosclerotic plaques: in vitro validation and in vivo evaluation. Ultrasound in Medicine & Biology. 40(5): 890-903.
- Z. Keshavarz-Motamed, J. Garcia, L. Kadem. (2013). Fluid dynamics of coarctation of the aorta and effect of bicuspid aortic valve. PLoS One. 8(8): e72394.
- Z. Keshavarz-Motamed, J. Garcia, N. Maftoon, E. Bedard, P. Chetaille, L. Kadem. (2012). A new approach for the evaluation of the severity of coarctation of the aorta using Doppler velocity index and effective orifice area: in vitro study and clinical implications. Journal of Biomechanics. 45(7): 1239-1245.
- Z. Keshavarz-Motamed, J. Garcia, P. Pibarot, L. Kadem. (2011). Modeling the impact of concomitant aortic stenosis and coarctation of the aorta on left ventricular workload. Journal of Biomechanics. 44(16): 2817-2825.
- Z. Keshavarz-Motamed, L. Kadem, A. Dolatabadi. (2010). Effects of dynamic contact angle on numerical modeling of electrowetting in parallel plate microchannels. Journal of Microfluidics and Nanofluidics. 8(1): 47-56.
- Z. Keshavarz-Motamed, L. Kadem. (2010). Pulsatile flow in a curved tube with coexisting model of aortic stenosis and coarctationof the aorta. Medical Engineering and Physics. 33(3): 315-324.

 

Available Positions

There are multiple MSc and PhD positions available in my group. There are many potential projects in the lab for undergraduates interested in independent studies, summer positions and honours projects. Interested students should apply by email (motamedz@mcmaster.ca or zahra_km@mit.edu) and include a brief description of their research interests, transcripts, curriculum vitae and references. Graduate students and postdoctoral fellows with external funding are encouraged to contact Dr. Motamed to discuss mutual research interests.